Article
Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence.
Alcoholism, clinical and experimental research - 1 Mar 2004
Huang San-Yuan, Lin Wei-Wen, Ko Huei-Chen, Lee Jia-Fu, Wang Tso-Jen, Chou Yuan-Hwa, Yin Shih-Jiun, Lu Ru-Band
Abstract excerpt
BACKGROUND: The role of the dopamine D2 receptor (DRD2) gene in the development of alcohol abuse or dependence is controversial. The controversy is due in part to the disparate definitions pertaining to the control groups used and to the definitions of subtypes in alcohol dependence. In the Han Chinese population, the alcohol dehydrogenase 1B*2/*2 (ADH1B*2/*2) genotype and the aldehyde dehydrogenase 2*2 (ALDH2*2)...
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