Article
Genetic association of DRD2 polymorphisms with anxiety scores among alcohol-dependent patients.
Biochemical and biophysical research communications - 11 Jul 2008
Joe Keun-Ho, Kim Dai-Jin, Park Byung Lae, Yoon Sujung, Lee Hae-Kook, Kim Tae-Suk, Cheon Young-Hoon, Gwon Do-Hoon, Cho Sung-Nam, Lee Hye Won, Namgung Suk, Shin Hyoung Doo
Abstract excerpt
The dopaminergic neurotransmission system is one of the major factors in development of alcoholism and also contributes to anxiety and depression. In this study, the associations of the dopamine receptor type 2 (DRD2) polymorphisms with the symptoms of anxiety were analyzed. A total of 573 alcoholics and 273 controls were enrolled in the study from the Korean population. Five DRD2 SNPs, including -32869 A>G,...
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