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Impact of a multi-nutrient diet on cognition, brain metabolism, hemodynamics, and plasticity in apoE4 carrier and apoE knockout mice.

Brain structure & function - 1 Sept 2014

Jansen Diane, Zerbi Valerio, Janssen Carola I F, van Rooij Daan, Zinnhardt Bastian, Dederen Pieter J, Wright Alan J, Broersen Laus M, Lütjohann Dieter, Heerschap Arend, Kiliaan Amanda J

Abstract excerpt

Lipid metabolism and genetic background together strongly influence the development of both cardiovascular and neurodegenerative diseases like Alzheimer's disease (AD). A non-pharmacological way to prevent the genotype-induced occurrence of these pathologies is given by dietary behavior. In the present study, we tested the effects of long-term consumption of a specific multi-nutrient diet in two models for...

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PMID: 23832599
DOI: 10.1007/s00429-013-0606-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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