Article
Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia.
EMBO molecular medicine - 1 Aug 2013
Regalo Gonçalo, Leutz Achim
Abstract excerpt
Initiating neoplastic cell transformation events are of paramount importance for the comprehension of regeneration and vanguard oncogenic processes but are difficult to characterize and frequently clinically overlooked. In epithelia, pre-neoplastic transformation stages are often distinguished by the appearance of phenotypic features of another differentiated tissue, termed metaplasia. In haemato/lymphopoietic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
