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Transdifferentiation in developmental biology, disease, and in therapy

18 Oct 2007

Abstract excerpt

Transdifferentiation (or metaplasia) refers to the conversion of one cell type to another. Because transdifferentiation normally occurs between cells that arise from the same region of the embryo, understanding the molecular and cellular events in cell type transformations may help to explain the mechanisms underlying normal development. Here we review examples of transdifferentiation in nature focusing on the...

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PMID: 17948254
DOI: 10.1002/dvdy.21336

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