Article
Race, genetic ancestry and response to antidepressant treatment for major depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2013
Murphy Eleanor, Hou Liping, Maher Brion S, Woldehawariat Girma, Kassem Layla, Akula Nirmala, Laje Gonzalo, McMahon Francis J
Abstract excerpt
The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study revealed poorer antidepressant treatment response among black compared with white participants. This racial disparity persisted even after socioeconomic and baseline clinical factors were taken into account. Some studies have suggested genetic contributions to this disparity, but none have attempted to disentangle race and genetic ancestry....
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