Article
Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D.
PloS one - 1 Jan 2013
Adkins Daniel E, Souza Renan P, Aberg Karolina, Clark Shaunna L, McClay Joseph L, Sullivan Patrick F, van den Oord Edwin J C G
Abstract excerpt
Only a subset of patients will typically respond to any given prescribed drug. The time it takes clinicians to declare a treatment ineffective leaves the patient in an impaired state and at unnecessary risk for adverse drug effects. Thus, diagnostic tests robustly predicting the most effective and safe medication for each patient prior to starting pharmacotherapy would have tremendous clinical value. In this...
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