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Article

Contribution of common genetic variants to antidepressant response.

Biological psychiatry - 1 Apr 2013

Tansey Katherine E, Guipponi Michel, Hu Xiaolan, Domenici Enrico, Lewis Glyn, Malafosse Alain, Wendland Jens R, Lewis Cathryn M, McGuffin Peter, Uher Rudolf

Abstract excerpt

BACKGROUND: Pharmacogenetic studies aiming to personalize the treatment of depression are based on the assumption that response to antidepressants is a heritable trait, but there is no compelling evidence to support this. METHODS: We estimate the contribution of common genetic variation to antidepressant response with Genome-Wide Complex Trait Analysis in a combined sample of 2799 antidepressant-treated subjects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23237317
DOI: 10.1016/j.biopsych.2012.10.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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