Article
DNA repair systems in malignant mesothelioma.
Cancer letters - 22 Dec 2011
Toumpanakis Dimitrios, Theocharis Stamatios E
Abstract excerpt
Malignant mesothelioma (MM) is an aggressive tumor of serosal surfaces with increasing incidence and poor prognosis. Asbestos exposure is the main cause of MM and asbestos-induced DNA damage is critical for MM pathogenesis. The present review summarizes the implications of DNA repair systems in MM development, focusing on gene expression alterations and single nucleotide polymorphisms of genes encoding for DNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
