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Article

New pathogenic germline variants identified in mesothelioma.

Lung cancer (Amsterdam, Netherlands) - 1 May 2023

Belcaid Laila, Bertelsen Birgitte, Wadt Karin, Tuxen Ida, Spanggaard Iben, Højgaard Martin, Benn Sørensen Jens, Ravn Jesper, Lassen Ulrik, Cilius Nielsen Finn, Rohrberg Kristoffer, Westmose Yde Christina

Abstract excerpt

BACKGROUND: Mesothelioma (MM) is associated with asbestos exposure, tumor heterogeneity and aggressive clinical behavior. Identification of germline pathogenic variants (PVs) in mesothelioma is relevant for identifying potential actionable targets and genetic counseling. METHODS: 44 patients underwent whole exome sequencing (WES) or whole genome sequencing (WGS). Germline variants were selected according to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36944283
DOI: 10.1016/j.lungcan.2023.03.008

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