Article
Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid.
Biomaterials - 1 Oct 2013
Pedron Sara, Becka Eftalda, Harley Brendan A C
Abstract excerpt
Human glioblastoma multiforme (hGBM) is the most common, aggressive, and deadly form of brain cancer. A major obstacle to understanding the impact of extracellular cues on glioblastoma invasion is the absence of model matrix systems able to replicate compositional and structural elements of the glioma mass as well as the surrounding brain tissue. Contact with a primary extracellular matrix component in the brain,...
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