Article
Three-dimensional biomimetic hyaluronic acid hydrogels to investigate glioblastoma stem cell behaviors.
Biotechnology and bioengineering - 1 Feb 2020
Nakod Pinaki S, Kim Yonghyun, Rao Shreyas S
Abstract excerpt
Glioblastoma multiforme (GBM) is the deadliest form of primary brain tumor. GBM tumors are highly heterogeneous, being composed of tumor cells as well as glioblastoma stem cells (GSCs) that contribute to drug resistance and tumor recurrence following treatment. To develop therapeutic strategies, an improved understanding of GSC behavior in their microenvironment is critical. Herein, we have employed...
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