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Article

Two ENU-induced alleles of Atp2b2 cause deafness in mice.

PloS one - 1 Jan 2013

Carpinelli Marina R, Manning Michael G, Kile Benjamin T, Burt Rachel A, Rachel A Burt

Abstract excerpt

Over 120 loci are known to cause inherited hearing loss in humans. The deafness gene has been identified for only half of these loci. With the aim of identifying some of the remaining deafness genes, we performed an ethylnitrosourea mutagenesis screen for deaf mice. We isolated two mutants with semi-dominant hearing loss, Deaf11 and Deaf13. Both contained causative mutations in Atp2b2, which encodes the plasma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23826306
DOI: 10.1371/journal.pone.0067479
PMCID: PMC3691321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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