Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mouse models for human deafness: current tools for new fashions.

Trends in molecular medicine - 1 Sept 2002

Ahituv Nadav, Avraham Karen B

Abstract excerpt

Mouse models are one of the major tools used for discovery and characterization of genes for non-syndromic deafness in humans. The similarities between the mouse and human genomes, and between the physiology and morphology of their auditory systems, are striking. This article describes the latest mouse models, including spontaneous, 'knockout' and ENU (N-ethyl-N-nitrosourea)-induced mutants, and the recent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Deafness
Share to Disease Models, Animal
Share to Ear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Mutation

Source

Identifiers

PMID: 12223317
DOI: 10.1016/s1471-4914(02)02388-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mouse models for human deafness: current tools for new fashions.PMID 12223317Read ↗

A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment.Semantic proximity Read ↗

Identification and characterisation of new mouse models for hearing lossSemantic proximity Read ↗

Inherited hearing defects in mice.Semantic proximity Read ↗

Analysis of the mouse mutant Cloth-ears shows a role for the voltage-gated sodium channel Scn8a in peripheral neural hearing loss.Semantic proximity Read ↗

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.Semantic proximity Read ↗

Identification of 17 hearing impaired mouse strains in the TMGC ENU-mutagenesis screen.Semantic proximity Read ↗

Genetics of Hearing and DeafnessSemantic proximity Read ↗

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.Semantic proximity Read ↗

Paradigms and paradoxes: mouse (and human) models of genetic deafness.Semantic proximity Read ↗

ENU mutagenesis, a way forward to understand gene function.Semantic proximity Read ↗

Mouse models to study inner ear development and hereditary hearing loss.Semantic proximity Read ↗

Mouse mutagenesis-systematic studies of mammalian gene function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.