An information-theoretic machine learning approach to expression QTL analysis.

Abstract excerpt

Expression Quantitative Trait Locus (eQTL) analysis is a powerful tool to study the biological mechanisms linking the genotype with gene expression. Such analyses can identify genomic locations where genotypic variants influence the expression of genes, both in close proximity to the variant (cis-eQTL), and on other chromosomes (trans-eQTL). Many traditional eQTL methods are based on a linear regression model. In...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Artificial Intelligence
• Share to Gene Expression Regulation
• Share to Information Theory