Article
Improving eQTL Analysis Using a Machine Learning Approach for Data Integration: A Logistic Model Tree Solution.
Journal of computational biology : a journal of computational molecular cell biology - 1 Oct 2018
Beretta Stefano, Castelli Mauro, Gonçalves Ivo, Kel Ivan, Giansanti Valentina, Merelli Ivan
Abstract excerpt
Expression quantitative trait loci (eQTL) analysis is an emerging method for establishing the impact of genetic variations (such as single nucleotide polymorphisms) on the expression levels of genes. Although different methods for evaluating the impact of these variations are proposed in the literature, the results obtained are mostly in disagreement, entailing a considerable number of false-positive predictions....
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