Article
An integrated hierarchical Bayesian model for multivariate eQTL mapping.
Statistical applications in genetics and molecular biology - 12 Jul 2012
Scott-Boyer Marie Pier, Imholte Gregory C, Tayeb Arafat, Labbe Aurelie, Deschepper Christian F, Gottardo Raphael
Abstract excerpt
Recently, expression quantitative loci (eQTL) mapping studies, where expression levels of thousands of genes are viewed as quantitative traits, have been used to provide greater insight into the biology of gene regulation. Originally, eQTLs were detected by applying standard QTL detection tools (using a "one gene at-a-time" approach), but this method ignores many possible interactions between genes. Several other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
