Article
Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes.
The Journal of biological chemistry - 1 Oct 2004
Subramanian Vidya, Rothenberg Alexis, Gomez Carlos, Cohen Alex W, Garcia Anne, Bhattacharyya Sucharita, Shapiro Lawrence, Dolios Georgia, Wang Rong, Lisanti Michael P, Brasaemle Dawn L
Abstract excerpt
Perilipins, the major structural proteins coating the surfaces of mature lipid droplets of adipocytes, play an important role in the regulation of triacylglycerol storage and hydrolysis. We have used proteomic analysis to identify CGI-58, a member of the alpha/beta-hydrolase fold family of enzymes, as a component of lipid droplets of 3T3-L1 adipocytes. CGI-58 mRNA is highly expressed in adipose tissue and testes,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
