Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aim2 and Nlrp3 Are Dispensable for Vaccine-Induced Immunity against Francisella tularensis Live Vaccine Strain.

Infection and immunity - 16 Jun 2021

Alqahtani Maha, Ma Zhuo, Fantone Kayla, Malik Meenakshi, Bakshi Chandra Shekhar

Abstract excerpt

Francisella tularensis is a facultative, intracellular, Gram-negative bacterium that causes a fatal disease known as tularemia. Due to its extremely high virulence, ease of spread by aerosolization, and potential to be used as a bioterror agent, F. tularensis is classified by the CDC as a tier 1 category A select agent. Previous studies have demonstrated the roles of the inflammasome sensors absent in melanoma 2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Vaccines
Share to Francisella tularensis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Host-Pathogen Interactions

Share to Immunity, Humoral

Share to Immunization

Share to NLR Family, Pyrin Domain-Containing 3 Protein

Share to Tularemia

Share to Vaccines, Attenuated

Source

Open in PubMed Open full text

Identifiers

PMID: 33875472
DOI: 10.1128/IAI.00134-21
PMCID: PMC8208512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aim2 and Nlrp3 Are Dispensable for Vaccine-Induced Immunity against Francisella tularensis Live Vaccine Strain.PMID 33875472Read ↗

Comparative analysis of absent in melanoma 2-inflammasome activation in Francisella tularensis and Francisella novicidaSemantic proximity Read ↗

Repression of inflammasome by Francisella tularensis during early stages of infection.Semantic proximity Read ↗

Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation.Semantic proximity Read ↗

Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia.Semantic proximity Read ↗

Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence.Semantic proximity Read ↗

Adaptive Immunity to Francisella tularensis and Considerations for Vaccine DevelopmentSemantic proximity Read ↗

Identification of a live attenuated vaccine candidate for tularemia prophylaxis.Semantic proximity Read ↗

Single-cell resolution map of innate-like lymphocyte response to <i>Francisella tularensis</i> infection reveals MAIT cells’ role in protection from tularemia-like diseaseSemantic proximity Read ↗

Identification of a Novel Francisella tularensis Factor Required for Intramacrophage Survival and Subversion of Innate Immune ResponseSemantic proximity Read ↗

Vaccines against Francisella tularensis.Semantic proximity Read ↗

Antioxidant defenses of <i>Francisella tularensis</i> perturb Aim2 Inflammasome ActivationSemantic proximity Read ↗

IglG and IglI of the Francisella Pathogenicity Island Are Important Virulence Determinants of Francisella tularensis LVSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.