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Paraoxonase 1 (PON1) gene-108C>T and p.Q192R polymorphisms and arylesterase activity of the enzyme in patients with dementia.

Folia neuropathologica - 1 Jan 2013

Bednarska-Makaruk Małgorzata Ewa, Krzywkowski Tomasz, Graban Alla, Lipczyńska-Łojkowska Wanda, Bochyńska Anna, Rodo Maria, Wehr Hanna, Ryglewicz Danuta Krystyna

Abstract excerpt

Paraoxonase 1 (PON1) activity was determined using phenylacetate as substrate (arylesterase activity) in 304 individuals with dementia--136 recognised as probable Alzheimer's disease (AD), 64 as dementia of vascular origin (VaD) and 104 as mixed dementia (MD) and in 129 persons without symptoms of dementia and in a good general health. -108C>T polymorphism in the PON1 gene promoter and p.Q192R polymorphism in the...

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Source

Identifiers

PMID: 23821382
DOI: 10.5114/fn.2013.35953

Genes

PON1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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