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Article

Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity.

Cellular signalling - 1 Nov 2013

Chow Christina R, Suzuki Nobuchika, Kawamura Takeshi, Hamakubo Takao, Kozasa Tohru

Abstract excerpt

p115RhoGEF is a member of a family of Rho-specific guanine nucleotide exchange factors that also contains a regulator of G protein signaling homology domain (RH-RhoGEFs) that serves as a link between Gα13 signaling and RhoA activation. While the mechanism of regulation of p115RhoGEF by Gα13 is becoming well-known, the role of other regulatory mechanisms, such as post-translational modification or autoinhibition,...

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Identifiers

PMID: 23816534
DOI: 10.1016/j.cellsig.2013.06.012
PMCID: PMC4076829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity.PMID 23816534Read ↗

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