Article
HLA-E variants are associated with sustained virological response in HIV/hepatitis C virus-coinfected patients on hepatitis C virus therapy.
AIDS (London, England) - 15 May 2013
Guzmán-Fulgencio María, Berenguer Juan, Rallón Norma, Fernández-Rodríguez Amanda, Miralles Pilar, Soriano Vicente, Jiménez-Sousa María A, Cosín Jaime, Medrano José, García-Álvarez Mónica, López Juan C, Benito José M, Resino Salvador
Abstract excerpt
OBJECTIVES: To analyze whether human leukocyte antigen (HLA)-E allelic variants are associated with and may predict response to peg-interferon (IFN) alpha and ribavirin treatment in HIV/hepatitis C virus (HCV)-coinfected patients. DESIGN: Retrospective follow-up study. METHODS: We studied 321 naive patients who started HCV treatment. HLA-E genotyping was performed by restriction fragment length polymorphism. A...
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