Article
The host HLA-A*02 allele is associated with the response to pegylated interferon and ribavirin in patients with chronic hepatitis C virus infection.
Archives of virology - 1 Apr 2015
Wang Meng, Li Jian-Sheng, Ping Yu, Li Zhi-Qin, Wang Li-Ping, Guo Qian, Zhang Zhen, Yue Dong-Li, Wang Fei, Zhang Teng-Fei, Islam Mohammad Serajul, Zhang Yi
Abstract excerpt
Human leukocyte antigen (HLA) alleles are associated with both the progression of chronic hepatitis C (CHC) and the sustained virological response (SVR) to antiviral therapy. HLA-A*02 is the most common HLA allele in people of European/Caucasian descent and the Chinese and Japanese population. Therefore, we investigated whether HLA-A*02 expression is associated with disease outcome in Chinese CHC patients. Three...
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