Article
Human leukocyte antigen class I alleles can predict response to pegylated interferon/ribavirin therapy in chronic hepatitis C Egyptian patients.
Archives of Iranian medicine - 1 Feb 2013
Farag Raghda E, Arafa Mona M, El-Etreby Shahira, Saudy Niveen S, Eldeek Basem S, El-Alfy Hatem A, Goda Inas F, Ali Rabab M
Abstract excerpt
BACKGROUND: Racial differences and broad spectrum response to anti-hepatitis C (anti-HCV) therapy suggest a possible role for host genetic diversity in treatment outcomes. We aim to determine the association and predictive value of certain human leukocyte antigen (HLA) class I alleles with either susceptibility to viral clearance or persistence following pegylated interferon (Peg-IFN) plus ribavirin therapy in...
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