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Article

SNPs located at CpG sites modulate genome-epigenome interaction.

Epigenetics - 1 Aug 2013

Zhi Degui, Aslibekyan Stella, Irvin Marguerite R, Claas Steven A, Borecki Ingrid B, Ordovas Jose M, Absher Devin M, Arnett Donna K

Abstract excerpt

DNA methylation is an important molecular-level phenotype that links genotypes and complex disease traits. Previous studies have found local correlation between genetic variants and DNA methylation levels (cis-meQTLs). However, general mechanisms underlying cis-meQTLs are unclear. We conducted a cis-meQTL analysis of the Genetics of Lipid Lowering Drugs and Diet Network data (n = 593). We found that over 80% of...

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Identifiers

PMID: 23811543
DOI: 10.4161/epi.25501
PMCID: PMC3883783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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