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Article

A novel lamin A/C mutation in a family with dilated cardiomyopathy, prominent conduction system disease, and need for permanent pacemaker implantation.

American heart journal - 1 Dec 2002

Hershberger Ray E, Hanson Emily L, Jakobs Petra M, Keegan Hugh, Coates Kelly, Bousman Sylvia, Litt Michael

Abstract excerpt

BACKGROUND: The LMNA gene, which encodes the nuclear envelope protein lamin A/C, is thought to be the most common of 8 autosomal disease genes implicated in familial dilated cardiomyopathy (FDC). Each family reported to date has a unique mutation and variable degrees of cardiac conduction system, dilated cardiomyopathy, or skeletal muscle disease. METHODS AND RESULTS: Coding regions of the LMNA gene were screened...

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Share to Arrhythmias, Cardiac
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lamin Type A

Share to Mutation, Missense

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Source

Identifiers

PMID: 12486434
DOI: 10.1067/mhj.2002.126737

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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