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Article

The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy.

Developmental cell - 15 Jul 2013

Mao Kai, Wang Ke, Liu Xu, Klionsky Daniel J

Abstract excerpt

As the cellular power plant, mitochondria play a significant role in homeostasis. To maintain the proper quality and quantity of mitochondria requires both mitochondrial degradation and division. A selective type of autophagy, mitophagy, drives the degradation of excess or damaged mitochondria, whereas division is controlled by a specific fission complex; however, the relationship between these two processes,...

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Identifiers

PMID: 23810512
DOI: 10.1016/j.devcel.2013.05.024
PMCID: PMC3720741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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