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Article

Mitochondria removal by autophagy

8 Feb 2011

Abstract excerpt

Mitochondrial dysfunction has severe cellular consequences and is linked with neurodegenerative diseases and aging. Maintaining a healthy population of mitochondria is thus essential for proper cellular homeostasis. Several strategies have evolved to prevent and limit mitochondria damage, and macroautophagy plays a role in degrading superfluous or severely damaged mitochondria. Selective removal of mitochondria...

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PMID: 21252623
DOI: 10.4161/auto.7.3.14502

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