Patterns of cerebral amyloid angiopathy define histopathological phenotypes in A lzheimer's disease

Abstract excerpt

AIMS: Pathological heterogeneity of Aβ deposition in senile plaques (SP) and cerebral amyloid angiopathy (CAA) in Alzheimer's disease (AD) has been long noted. The aim of this study was to classify cases of AD according to their pattern of Aβ deposition, and to seek factors which might predict, or predispose towards, this heterogeneity. METHODS: The form, distribution and severity of Aβ deposition (as SP and/or...

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