Article

O2‐03‐03: Phenotypic and genetic subclassification of Alzheimer's disease

2009-06-25

Abstract excerpt

Two different types of Alzheimer's disease (AD)-related cerebral amyloid angiopathy (CAA) can be distinguished by the presence or absence of capillary amyloid β-protein (Aβ)-deposition. Genetically, CAA-type 1 with capillary CAA is strongly associated with the apolipoprotein E (APOE) ϵ4-allele, while CAA-type 2 lacking capillary Aβ did not show this association. The objective of this study was to test whether ther...

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Alzheimer's disease research and treatments

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Literature Corpus work: 6f89a7cd-c0a4-5b60-a286-a9aa3cda7b17
DOI: 10.1016/j.jalz.2009.05.336

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