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Article

Protein kinase A and phosphodiesterase-4D3 binding to coding polymorphisms of cardiac muscle anchoring protein (mAKAP).

Journal of molecular biology - 23 Sept 2013

Rababa'h Abeer, Craft John W, Wijaya Cori S, Atrooz Fatin, Fan Qiying, Singh Sonal, Guillory Ashley N, Katsonis Panagiotis, Lichtarge Olivier, McConnell Bradley K

Abstract excerpt

Protein kinase A (PKA) substrate phosphorylation is facilitated through its co-localization with its signaling partner by A-kinase anchoring proteins (AKAPs). mAKAP (muscle-selective AKAP) localizes PKA and its substrates such as phosphodiesterase-4D3 (PDE4D3), ryanodine receptor, and protein phosphatase 2A (PP2A) to the sarcoplasmic reticulum and perinuclear space. The genetic role of mAKAP, in modulating...

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Identifiers

PMID: 23806656
DOI: 10.1016/j.jmb.2013.06.014
PMCID: PMC3808176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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