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Article

Genetic Susceptibility, Change in Physical Activity, and Long-term Weight Gain.

Diabetes - 1 Oct 2017

Wang Tiange, Huang Tao, Heianza Yoriko, Sun Dianjianyi, Zheng Yan, Ma Wenjie, Jensen Majken K, Kang Jae H, Wiggs Janey L, Pasquale Louis R, Rimm Eric B, Manson JoAnn E, Hu Frank B, Willett Walter C, Qi Lu

Abstract excerpt

Whether change in physical activity over time modifies the genetic susceptibility to long-term weight gain is unknown. We calculated a BMI-genetic risk score (GRS) based on 77 BMI-associated single nucleotide polymorphisms (SNPs) and a body fat percentage (BF%)-GRS based on 12 BF%-associated SNPs in 9,390 women from the Nurses' Health Study (NHS) and 5,291 men from the Health Professionals Follow-Up Study (HPFS)....

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PMID: 28701334
DOI: 10.2337/db17-0071
PMCID: PMC5606317

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NHS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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