Article
Genetic polymorphisms in the hypothalamic pathway in relation to subsequent weight change--the DiOGenes study.
PloS one - 24 Feb 2011
Du Huaidong, Vimaleswaran Karani S, Angquist Lars, Hansen Rikke D, van der A Daphne L, Holst Claus, Tjønneland Anne, Overvad Kim, Jakobsen Marianne Uhre, Boeing Heiner, Meidtner Karina, Palli Domenico, Masala Giovanna, Bouatia-Naji Nabila, Saris Wim H M, Feskens Edith J M, Wareham Nicolas J, Sørensen Thorkild I A, Loos Ruth J F
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in genes encoding the components involved in the hypothalamic pathway may influence weight gain and dietary factors may modify their effects. AIM: We conducted a case-cohort study to investigate the associations of SNPs in candidate genes with weight change during an average of 6.8 years of follow-up and to examine the potential effect modification by glycemic...
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