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Article

Inverse relationship between a genetic risk score of 31 BMI loci and weight change before and after reaching middle age.

International journal of obesity (2005) - 1 Feb 2016

Rukh G, Ahmad S, Ericson U, Hindy G, Stocks T, Renström F, Almgren P, Nilsson P M, Melander O, Franks P W, Orho-Melander M

Abstract excerpt

BACKGROUND/OBJECTIVE: Genome-wide-association studies have identified numerous body mass index (BMI)-associated variants, but it is unclear how these relate to weight gain in adults at different ages. METHODS: We examined the association of a genetic risk score (GRS), consisting of 31 BMI-associated variants, with an annual weight change (AWC) and a substantial weight gain (SWG) of 10% by comparing self-reported...

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Identifiers

PMID: 26374450
DOI: 10.1038/ijo.2015.180
PMCID: PMC4753358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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