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Article

Gene-gene interactions in the NOD mouse model of type 1 diabetes.

Advances in immunology - 1 Jan 2008

Ridgway William M, Peterson Laurence B, Todd John A, Rainbow Dan B, Healy Barry, Burren Oliver S, Wicker Linda S

Abstract excerpt

Human genome wide association studies (GWAS) have recently identified at least four new, non-MHC-linked candidate genes or gene regions causing type one diabetes (T1D), highlighting the need for functional models to investigate how susceptibility alleles at multiple common genes interact to mediate disease. Progress in localizing genes in congenic strains of the nonobese diabetic (NOD) mouse has allowed the...

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Identifiers

PMID: 19111166
DOI: 10.1016/S0065-2776(08)00806-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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