Article

Immunologic Drivers and Restraints in Colitis-Associated Colorectal Cancer

2026-03-27

Abstract excerpt

Inflammatory bowel diseases (IBD), encompassing ulcerative colitis and Crohn’s dis-ease, are associated with an increased risk of colorectal cancer through mechanisms driven by persistent mucosal inflammation. Chronic inflammatory signaling, recurrent epithelial injury, and altered tissue repair processes progressively reshape the intesti-nal microenvironment, promoting genomic instability and facilitating the dev...

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Literature Corpus work: 4934c9f9-a5cd-5c80-bb4b-ed3c9477c1cc
DOI: 10.20944/preprints202603.2208.v1

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