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Article

Association of functional polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 genes with colorectal cancer.

International journal of cancer - 10 Dec 2002

Hinoda Yuji, Okayama Naoko, Takano Naofumi, Fujimura Kozue, Suehiro Yutaka, Hamanaka Yuichiro, Hazama Shoichi, Kitamura Yutaka, Kamatani Naoyuki, Oka Masaaki

Abstract excerpt

Matrix metalloproteinase (MMP)-1 and MMP-3 genes are associated with tumor cell invasion and metastasis with their promoter polymorphisms influencing the level of transcription. Our study explored the association of these polymorphisms with colorectal cancer risk in a Japanese population. DNA was extracted from peripheral blood of 101 patients with colorectal cancer and 127 age- and gender-matched healthy...

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PMID: 12432557
DOI: 10.1002/ijc.10750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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