Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel genetic locus modulates infarct volume independently of the extent of collateral circulation.

Physiological genomics - 3 Sept 2013

Chu Pei-Lun, Keum Sehoon, Marchuk Douglas A

Abstract excerpt

In the mouse model of permanent, middle cerebral artery occlusion, infarct volume varies widely across inbred strains but generally is inversely correlated with collateral vessel number. However, we also observed certain mouse strains that share similar collateral vessel anatomy but exhibit significantly different infarct volume. To identify genetic factors determining infarct volume in a collateral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Infarction
Share to Brain Ischemia
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C3H

Share to Mice, Inbred C57BL

Share to Protein Tyrosine Phosphatases, Non-Receptor

Share to Quantitative Trait Loci

Share to Scavenger Receptors, Class A

Source

Open in PubMed Open full text

Identifiers

PMID: 23800850
DOI: 10.1152/physiolgenomics.00063.2013
PMCID: PMC3763066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel genetic locus modulates infarct volume independently of the extent of collateral circulation.PMID 23800850Read ↗

Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke.Semantic proximity Read ↗

Identification of novel neuroprotective loci modulating ischemic stroke volume in a cross between wild-derived inbred mouse strainsSemantic proximity Read ↗

A neuroprotective locus modulates ischemic stroke infarction independent of collateral vessel anatomySemantic proximity Read ↗

Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation.Semantic proximity Read ↗

Large differences in collateral blood vessel abundance among individuals arise from multiple genetic variantsSemantic proximity Read ↗

Wide genetic variation in the native pial collateral circulation is a major determinant of variation in severity of stroke.Semantic proximity Read ↗

Genetic architecture underlying variation in extent and remodeling of the collateral circulation.Semantic proximity Read ↗

<i>Ide</i> copy number variant does not influence lesion size and mortality in two C57BL/6J mouse models of cerebrovascular ischemia nor in human cerebrovascular disease. An exploratory studySemantic proximity Read ↗

Polygenic Control of Carotid Atherosclerosis in a BALB/cJ × SM/J Intercross and a Combined Cross Involving Multiple Mouse Strains.Semantic proximity Read ↗

Integrative Mouse and Human Studies Implicate ANGPT1 and ZBTB7C as Susceptibility Genes to Ischemic Injury.Semantic proximity Read ↗

Role of Genetic Variation in Collateral Circulation in the Evolution of Acute Stroke: A Multimodal Magnetic Resonance Imaging Study.Semantic proximity Read ↗

Strain-dependent variation in collateral circulatory function in mouse hindlimb.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.