Article
Epithelial ovarian cancer: rationale for changing the one-fits-all standard treatment regimen to subtype-specific treatment.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Mar 2014
Despierre Evelyn, Yesilyurt Betül T, Lambrechts Sandrina, Johnson Nick, Verheijen René, van der Burg Maria, Casado Antonio, Rustin Gordon, Berns Els, Leunen Karin, Amant Frédéric, Moerman Philippe, Lambrechts Diether, Vergote Ignace
Abstract excerpt
OBJECTIVE: Epithelial ovarian cancers (EOCs) are, although still treated as a single disease entity, often classified into type I tumors (low-grade serous, mucinous, endometrioid, clear cell) and type II tumors (high-grade serous, undifferentiated cancers, carcinosarcomas). The aim of our study was to determine the incidence, clinical relevance, and prognostic and predictive impact of somatic mutations in both...
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