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Article

Mutational Aberrations Detected in Mucinous Epithelial Ovarian Cancer of Asian Women.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Mar 2018

Chay Wen Yee, Kwok Li Lian, Tiong Wen Ning, Krisna Sai Sakktee, Lim Kiat Hon, Iyer N Gopalkrishna, Goh Liang Kee, Tan Daniel Shao-Weng

Abstract excerpt

BACKGROUND: Mucinous epithelial ovarian cancers (mEOCs) respond poorly to conventional chemotherapy and have a poor prognosis in advanced stages. The genomic landscape for mEOC in the Asian settings is ill defined. We seek to identify various mutational aberrations present in mEOC and correlate them with clinical outcomes. METHODS: A total of 199 cases of mEOC were identified from a prospectively maintained...

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Topics

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Share to Adenocarcinoma, Mucinous
Share to Disease-Free Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Immunohistochemistry

Share to In Situ Hybridization

Share to Ovarian Neoplasms

Share to Proto-Oncogene Proteins p21(ras)

Share to Receptor, ErbB-2

Source

Identifiers

PMID: 29465505
DOI: 10.1097/IGC.0000000000001138

Genes

KRAS
HRAS
KIT
MET
NRAS
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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