Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls.

PloS one - 1 Jan 2013

Zhang Huiping, Wang Fan, Kranzler Henry R, Zhao Hongyu, Gelernter Joel

Abstract excerpt

The increased vulnerability to alcohol dependence (AD) seen in individuals with childhood adversity (CA) may result in part from CA-induced epigenetic changes. To examine CA-associated DNA methylation changes in AD patients, we examined peripheral blood DNA methylation levels of 384 CpGs in promoter regions of 82 candidate genes in 279 African Americans [AAs; 88 with CA (70.5% with AD) and 191 without CA (38.2%...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Aldehyde Dehydrogenase
Share to Aldehyde Dehydrogenase 1 Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child Abuse

Share to Receptors, Nicotinic

Share to Receptors, Opioid

Share to Retinal Dehydrogenase

Share to RGS Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23799031
DOI: 10.1371/journal.pone.0065648
PMCID: PMC3683055

Genes

OPRL1
RGS19
CHRNA5
PENK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls.PMID 23799031Read ↗

Genome-wide DNA methylation analysis in alcohol dependence.Semantic proximity Read ↗

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Semantic proximity Read ↗

An investigation of child maltreatment and epigenetic mechanisms of mental and physical health risk.Semantic proximity Read ↗

Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes.Semantic proximity Read ↗

Genomic influences on alcohol problems in a population-based sample of young adults.Semantic proximity Read ↗

DNA methylation signature of human fetal alcohol spectrum disorderSemantic proximity Read ↗

Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations.Semantic proximity Read ↗

Human genetics and epigenetics of alcohol use disorder.Semantic proximity Read ↗

Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes.Semantic proximity Read ↗

Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence.Semantic proximity Read ↗

A DNA methylation biomarker of alcohol consumptionSemantic proximity Read ↗

Epigenetics of alcohol use disorder-A review of recent advances in DNA methylation profiling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.