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Article

Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes.

Human genetics - 1 Sept 2014

Zhang Huiping, Wang Fan, Kranzler Henry R, Yang Can, Xu Hongqin, Wang Zuoheng, Zhao Hongyu, Gelernter Joel

Abstract excerpt

Interaction of DNA methylation and sequence variants that are methylation quantitative trait loci (mQTLs) may influence susceptibility to diseases such as alcohol dependence (AD). We used genome-wide genotype data from 268 African Americans (AAs: 129 AD cases and 139 controls) and 143 European Americans (EAs: 129 AD cases and 14 controls) to identify mQTLs that were associated with promoter CpGs in 82 AD risk...

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Source

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Identifiers

PMID: 24889829
DOI: 10.1007/s00439-014-1452-2
PMCID: PMC4127343

Genes

ADH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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