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Article

Recent advances in p97/VCP/Cdc48 cellular functions.

Biochimica et biophysica acta - 1 Jan 2012

Yamanaka Kunitoshi, Sasagawa Yohei, Ogura Teru

Abstract excerpt

p97/VCP/Cdc48 is one of the best-characterized type II AAA (ATPases associated with diverse cellular activities) ATPases. p97 is suggested to be a ubiquitin-selective chaperone and its key function is to disassemble protein complexes. p97 is involved in a wide variety of cellular activities. Recently, novel functions, namely autophagy and mitochondrial quality control, for p97 have been uncovered. p97 was...

Topics

Adenosine Triphosphatases
Animals
Antineoplastic Agents
Cell Cycle
Cell Cycle Proteins
Endoplasmic Reticulum-Associated Degradation
Humans
Mitochondria
Mutation
Myositis, Inclusion Body
Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proteolysis

Ubiquitinated Proteins

Valosin Containing Protein

Source

Identifiers

PMID: 21781992
DOI: 10.1016/j.bbamcr.2011.07.001

Genes

VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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