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Article

Association study of germline variants in CCNB1 and CDK1 with breast cancer susceptibility, progression, and survival among Chinese Han women.

PloS one - 1 Jan 2013

Li Yan, Chen Yi-Lin, Xie Yun-Tao, Zheng Li-Yuan, Han Ji-Yuan, Wang Hui, Tian Xin-Xia, Fang Wei-Gang

Abstract excerpt

The CCNB1 and CDK1 genes encode the proteins of CyclinB1 and CDK1 respectively, which interact with each other and are involved in cell cycle regulation, centrosome duplication and chromosome segregation. This study aimed to investigate whether the genetic variants in these two genes may affect breast cancer (BC) susceptibility, progression, and survival in Chinese Han population using haplotype-based analysis. A...

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Source

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Identifiers

PMID: 24386390
DOI: 10.1371/journal.pone.0084489
PMCID: PMC3873991

Genes

CDK1
CCNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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