Article
Influence of the CYP2J2 Gene Polymorphisms on Chronic Obstructive Pulmonary Disease Risk in the Chinese Han Population.
Archivos de bronconeumologia - 1 Nov 2020
Lu Hui, Yang Yixiu, Chen Xianghong, Wu Cibing, Zhao Jie, Feng Qiong, Zhou Xiaoli, Xu Dongchuan, Li Quanni, Niu Huan, He Ping, Liu Jianfang, Yao Hongxia, Ding Yipeng
Abstract excerpt
INTRODUCTION: Cytochrome P450 (CYP) 2J2 is a major enzyme that controls epoxyeicosatrienoic acids biosynthesis, which may play a role in chronic obstructive pulmonary disease (COPD) development. In this study, we aimed to assess the influence of CYP2J2 polymorphisms with COPD susceptibility. MATERIAL AND METHODS: A case-control study enrolled 313 COPD cases and 508 controls was to investigate the association...
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