Article
Genetic variation in the beta-2 adrenergic receptor (ADRB2) predicts functional gastrointestinal diagnoses and poorer health-related quality of life.
Alimentary pharmacology & therapeutics - 1 Aug 2013
Kushnir V M, Cassell B, Gyawali C P, Newberry R D, Kibe P, Nix B D, Sabzpoushan A, Kanuri N D, Sayuk G S
Abstract excerpt
BACKGROUND: The beta-2 adrenergic receptor (ADRB2) is an important target for epinephrine, a neurotransmitter in pain signalling. ADRB2 haplotypes affect receptor expression and ligand response, and have been linked to painful non-GI disorders. AIMS: To assess whether ADRB2 polymorphisms (rs10427...
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