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Article

G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia.

Gastroenterology - 1 Apr 2004

Holtmann Gerald, Siffert Winfried, Haag Sebastian, Mueller Norbert, Langkafel Mathias, Senf Wolfgang, Zotz Rainer, Talley Nicholas J

Abstract excerpt

BACKGROUND & AIMS: In patients with functional dyspepsia, altered alpha-adrenoreceptor function and depression are prevalent, features that are linked to a G-protein beta 3 (GNB3) subunit gene polymorphism (C825T). We aimed to assess the association of specific G-protein beta 3 subunit genotypes...

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Source

Identifiers

PMID: 15057736
DOI: 10.1053/j.gastro.2004.01.006

Genes

GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15057736-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia.PMID 15057736Read ↗

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Functional dyspepsia is associated with GNβ3 C825T and CCK-AR T/C polymorphism.Semantic proximity Read ↗

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Is there an association between GNbeta3-C825T genotype and lower functional gastrointestinal disorders?Semantic proximity Read ↗

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Homozygous 825T allele of the GNB3 protein influences the susceptibility of Japanese to dyspepsia.Semantic proximity Read ↗

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