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Article

Candidate genes and sensory functions in health and irritable bowel syndrome.

American journal of physiology. Gastrointestinal and liver physiology - 1 Aug 2008

Camilleri Michael, Busciglio Irene, Carlson Paula, McKinzie Sanna, Burton Duane, Baxter Kari, Ryks Michael, Zinsmeister Alan R

Abstract excerpt

Adrenergic and serotonergic (ADR-SER) mechanisms alter gut (GI) function; these effects are mediated through G protein transduction. Candidate genetic variations in ADR-SER were significantly associated with somatic scores in irritable bowel syndrome (IBS) and gastric emptying but not small bowel or colonic transit. Our aim was to assess whether candidate ADR-SER genes are associated with motor and sensory GI...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Adrenergic, alpha-2

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Share to Serotonin Plasma Membrane Transport Proteins

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Source

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Identifiers

PMID: 18511740
DOI: 10.1152/ajpgi.90202.2008
PMCID: PMC2519854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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