Article
A survey of functional dyspepsia in 361,360 individuals: Phenotypic and genetic cross-disease analyses.
Neurogastroenterology and motility - 1 Jun 2022
Garcia-Etxebarria Koldo, Carbone Florencia, Teder-Laving Maris, Pandit Anita, Holvoet Lieselot, Thijs Vincent, Lemmens Robin, Bujanda Luis, Franke Andre, Zöllner Sebastian, Boehnke Michael, Zawistowski Matthew, Esko Tonu, Jan Tack, D'Amato Mauro
Abstract excerpt
BACKGROUND: Functional dyspepsia (FD) is a common gastrointestinal condition of poorly understood pathophysiology. While symptoms' overlap with other conditions may indicate common pathogenetic mechanisms, genetic predisposition is suspected but has not been adequately investigated. METHODS: Using healthcare, questionnaire, and genetic data from three large population-based biobanks (UK Biobank, EGCUT, and MGI),...
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