Article
Protein trafficking abnormalities in Drosophila tissues with impaired activity of the ZIP7 zinc transporter Catsup.
Development (Cambridge, England) - 1 Jul 2013
Groth Casper, Sasamura Takeshi, Khanna Mansi R, Whitley Michael, Fortini Mark E
Abstract excerpt
Developmental patterning requires the precise interplay of numerous intercellular signaling pathways to ensure that cells are properly specified during tissue formation and organogenesis. The spatiotemporal function of the Notch signaling pathway is strongly influenced by the biosynthesis and intracellular trafficking of signaling components. Receptors and ligands must be trafficked to the cell surface where they...
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